I do it all the time! I refuse to do bindings by hand. I ahve had the best sucess using the inviasble thread from Homesew or Clotilde. Do be careful winding the bobbin, go slow do not stretch the thread. Also use a cone holder( or jar/coffee mug) for the top thread , and put it as far away from the machine as you can. It needs to relax for a bit before going through your machine. I use a smaller needle as the thread is quite fine.
To avoid the little ends , trim the starting thread after you sew a few inches , as they are tough to find when the quilt is done.