It depends on the quilt. If it is something that I think I might want to put into a show I machine stitch on the front, turn to the back, and hand stitch.
If it's a simple little quilt or one to be USED like a baby quilt, then I machine stitch to the back, turn to the front, and machine stitch the front OR I machine stitch to the front, turn to the back, and stitch-in-the-ditch from the front.