I prewash fabrics that can be prewashed. But, when I buy pre-cut noodles or squares, they can't be prewashed. Most of my quilts go to Project Linus. And :oops: I smoke. So before I send any quilt to PL, I wash it twice--regardless of whether it was prewashed. I wash it once in regular detergent in a regular wash cycle since I figure that's the way it will be treated once it has been received by a child. I put Downy in the rinse cycle to make it soft. Then I wash it one more time using only baking soda in the wash cycle and plain water in the rinse cyce to get rid of the smell of the fabric softener and any remaining smoke smells. As soon as it comes out of the dryer, I put it in a sealable plastic baggie. I work with a lady who has the nose of a hound-dog and when she can't smell any residuals on the quilts, I send it to PL.