It depends on what I'm sewing. Sometimes I sew blocks 1 & 2 together from rows 1 & 2, continuing in that manner throughout the quilt. Then I take those groups of 4 blocks and sew group 1 & 2 togther in both group group 1 row to group 2 row, and so on and so forth. When I am done, if the math all works out, HOPEFULLY, I will only have 4 quadrants to join.
Otherwise, I sew from left to right, and from top to bottom. Did I totally confuse you?