It depends on what you want. Do you want colors and pattern to stand out or quilting to stand out? I would do SID on connecting seams and then SID only in blocks that meet with stitching requirement as stated on batting package. (eg- batting should be quilted less that 3.5" apart.) I always use invesible thread on top and you can not see stitching or mistakes. This may be time consuming but I think will be well worth it. I recently did one that I wish I had taken time to do SID on all seams instead of large meandering. Oh well!