I have very sensitive skin and must watch what I use. Yes you can have a reaction even after using something for a long time. It is a tad pricey, but Clinique is very pure and I've never had a problem with their products. Aveeno is a great moisturizer for us with sensitive skin and the price is good too. Also as another member mentioned, Bare Minerals is very good for us folks with sensitive skin. Cetaphil is a very good cleanser for sensitive skin and it leaves your face clean and soft.