You use the dryer sheets AFTER you have used them in the dryer so they really don't have that much left in them. Then if you wash your quilt after you make it there is not too much chance for the average person to have a problem with any chemicals that are left in the dryer sheets-IMHO. I iron the dryer sheets flat, sew them together if I need them bigger, & cut them to size if need be with my rotary cutter.