This is one task I break up into small pieces. Once my HST are sewn and pressed, I put them neatly into a basket on the kitchen table along with rotary cutter and mat. Every time I walk past, I trim a certain number, say 10 or twelve or a blocks worth. Then back to chores, say throw a load of laundry in, feed the cat, etc.
Its not like I stop piecing while doing this, there's always more HSTs to piece, block to put together from the ones I've already trimmed, new pattern to look at. Hey, watch that chocolate around quilt pieces, ask me how I know.
What a rush the first time I put a quilt together this way. It was precise, the corners were already square and blocks and rows just went together like a dream