I would try making a small one with a light batting so you can see how heavy it is. The fleece can make it heavier.
I have found if I spray baste the fleece and just do straight line quilting, I don't have any issues quilting it on my home machine. If you do FMW, just make sure you lower the feed dogs. (And maybe put the fleece side on top.) The spray also helps to keep it from stretching.
I don't adjust my stitches at all.
Oh, some fleece has more stretch than others, so stretch it both directions before you buy. I would buy a heavier fleece with less stretch.
Good luck :)