If your frame has at least 3 rollers, you don't need to baste a quilt and many people "float" their tops so they only use 2 rollers. Pinning the backing on square to the takeup & payout rollers, stitching the batting to the backing, attaching your side tensioning straps or whatever method you use then getting the top securely tacked and square is all that is needed.
For computer quided designs; some people will baste a quilt that is all ready loaded on the frame with water soluble thread to pre-draw it in so that points will match up on their design.
How is it easier to load by using spray baste? The only time I've used spray baste on a quilt that was loaded on the frame was to help control borders and keep them from going wonky. Now I just run a line of stitching down the sides before quilting each pass.