What I have learned...I've tried just about every needle on the market I think. I use Roxanne needles - usually 11's or 12's. The only threader to use (particularly with 12's) is the Roxanne threaders - they hold up much better. As others have said, start threading with the end of thread farthest from the spool. Sometimes a slant definetly helps. I also really like Americana thread but it is a bit bulky. I also use Thread Heaven thread conditioner before threading my needle. Prefer it much more than beeswax. Keeps the tangles down to a dull roar also. If I set the thread aside for a bit I will re-condition. Good luck. Don't worry about stitch size just try to get consistent stitches. It will all come with time.