It doesn't matter which way. Accuquilt has a great web site that offers tips as well. Some of the dies have the shapes at an angle those are supposed to have the material layed on them at an angle to make the cutting correct; per web site. If you are nervous about it then test running some pape thru it first to see how it comes out. One tip that was given up here that I think is great is to outline the shapes with a sharpie so they are easier to see. I try to minimize the wasted material so this is really important to me but if you don't care then cut the material the size of the die and it'll cover the whole thing and you'll be good. Remember to watch the grain of fabric; it will change the size of the block if you don't. Some fabrics I starch before working with them to help minimize stretching