I have not read the several pages of responses to your post, so if this is a repeat, I apologize.
As someone who has worn corrective lenses for 65 years, I can tell you that it's time for you to get an eye exam! Also, if you are truly focused on your applique, you might not be blinking enough; then your eyes will dry out & vision will blur, etc., etc. Sometimes I have to remind myself to blink when I'm doing hand quilting; since that is the only time I have that problem, I've concluded that it's because I'm so focused that I overwhelm my natural instinct to blink.