Our quilting group quilts for others. We are currently swearing at, I mean, working on a quilt that is double knit, sashed with cotton and batted and backed in the usual way. It is a nightmare to hand quilt. If you decide to use double knit, just use two layers of it, do not use a batting, and whatever you do, do not hand quilt it. Just tie it, or better yet, make a rag quilt as you go.
Been there, done that.