There are many different types of thread on the large spools, so yes, make sure you get what you want to use in your sewing. As far as having to stop and wind bobbins, I would suggest to some of you out there to try prewound bobbins. I know they sound expensive but they hold a great deal more thread on them than a bobbin you wind at home. Take a look at the Superior Thread web site. There is a wealth of information on this site.
Happy Sewing!