Hi,
Years ago I had two large floor frames. I now use two different standing hoops. When I was using the floor frames I also used a rolling office chair. The thing I learned about quilting on those frames was how to use both hands. I am right handed but I can quilt with either hand whichever is the most comfortable. I wear a long leather thimble on my right middle finger and a short leather thimbe on my left thumb. I quilt at our local Senior center once a week for a couple of hours and we are using a floor hoop there. It took a little getting used to but now I have no problem using both hands.
Having learned to play the piano and touch type may have helped me use both hands with ease better than someone who does neither.
I no longer have space for the floor frames. Sold them years ago.