When my sister passed away, her husband gave me two quilts that our Mom or grandmother made. She was a smoker and they reeked of smoke. I put them in the bathtub and used a quilt cleaner that comes in a cloth bag. I let it soak, rinsed it, sniffed, and did it again. Next day, I rinsed it, sniffed and it still stunk. I rinsed it again and poured a box of baking powder on it, let it soak and rinsed. I am allergic to smoke and I have the most sensitive sniffer ever. I resoaked it in a second box of baking powder and rinsed it and finally it did not smell. I actually thought I was going to have to get rid of them because I did not think the smell would ever come out. Don't give up, just keep soaking it. In the first two washings, the water was so yellow. This took 4-5 days. The quilt still smells good.