Being left handed has it's challenges. For cutters, I simply moved the position of the blade. Holding the cutter in your left hand, position the blade so that it's on the inside - facing your right. I use the markings on the ruler rather than those on the mat but I still have to look twice at the lines on it before I cut. The first cut to insure a straight line is always the hardest for me. And securing the ruler so that it doesn't slip is so important. I don't have as much strength in my right hand so standing up is necessary most of the time to get good pressure and I always make sure my pinky and ring finger are off the ruler while the rest of my hand is holding it down. Scissors are a pain that I've gotten used to. Fiskars has some that are spring loaded that you do not need to cram your fingers in the wrong holes. Us lefties just find a way to make it work for our needs. Just keep in mind that there are more and more of us -- we are the only ones in our RIGHT mind!