Been a lefty all my life, not that my Dad didn't try to change me, it didn't work! ! I have sewn all my life and have little to no problems. Own lots of rotary cutters and my favorite one is by Martelli. They are ergonomically designed for maximum confort, for left or right handed, in several sizes. Take a look at their site: www.martellinotions.com or ourquiltingspace.com
Martelli Enterprises Inc.
5450 North W Street
Pensacola, Fl. 32505
(850) 433-1414
I hope this helps. I don't think you will be disappointed, once you learn how to use them.