I have left handed scissors and pinking scissors..don't seem to have a lot of problems with the rotary cutter but I cut standing and can access my table from both sides. I tried to do a quilting bee and it simply didn't work. I quilt alone if I do hand quilting. I have been lucky at home .. both my sons were lefties so my husband was the one that had to find the best place to sit..still makes me laugh to think about that!