I have used the 505 basting spray for a number of years and even tho' I am asthmatic I have never had any problems with it. I use it on my quilting table and use an ordinary wipe clean cloth to get rid of any over-spray, not that there's much as I have got my technique right now.
I have used it on all types of batting and had no problems at all. BTW the other great thing about it is that you can iron out an wrinkles as you along, just a warm iron and it doesn't harm the poly batting at all. :thumbup: