I pre wash everything in cold water before it goes into a quilt.
Once, while in Paducah, I ran into Mr. B from Benartex fabrics. He asked how I like their fabric. I told him that the designs were great, but I had a problem that nearly everything Benartex bleeds, except the tans. His exact reply was. "Well, that's the nature of the beast." and he walked away from me. I don't buy much Benartex anymore.
Some of us have bleeding problems and some don't. Even with the same fabric. I wonder if there might be some difference in the water--minerals, etc.