In Maryville, There is " The Rooster Quilt Shoppe" on 411 South at US 129 just about 5 miles on the south side of Maryville. A good selection can be found there.
The Cherry Pit in downtown Sevierville is actually owned by George and Jane Washington, hence the name Cherry Pit. Their is very nice and helpful, tons of fabrics and patterns.
Gatlinburg has "Mountain Stitches by Susan" out in the Glades Craft Area.
Exquisite Quilting is located between Sevierville and Knoxville on Highway 441.
Loose Threads in Harriman is a little further SW from Maryville and Knoxville, and is a great shop.
Pappy's Quilting is outside of Maryville on 411 North toward Sevierville.
I visit there often as it is only about 10 miles from me.
Machine Quilting by Iva has several rooms of all types of fabrics. A very large selection of batiks, charm packs and jelly rolls, a room of nothing but CW fabrics. Iva carries most of the major brands and is a very popular shop. All kinds of patterns, and the best part it is only about 3 - 4 miles from my home. Can you tell I buy a lot there..... ???
Holloway's is located in Cosby on US 321 outside of Gatlinburg going toward Newport. A bit out of the way and the layout is a bit crowded with her displays but still a good shop to visit. She has a bed with tons of completed quilts in the shop and all types of patterns, mostly her own designs.
There are others in smaller towns but it depends on the route you take to get to Knoxville / Gatlinburg. If interested let me know.