Do it all the time! I have some fabric that I fell in love with and bought every yard of it I could find. I fussy cut one piece and made a quilted greeting card for a lady that my husband worked for when he was a teen. She passed away four days after her birthday and I am so happy that she got to see her birthday card made from my super beautiful fabric. I like what tealady suggested, a whole cloth quilt could be the answer. Until then I just look at it each time I go into my sewing room and it makes me happy. We are all slightly bonkers aren't we?