I love tuxedo cats! She's a cutie. :)
My shelter kitty also hated being picked up when I got her--I adopted her as a "young adult" cat, and she would scream bloody murder and struggle wildly anytime you picked her up. (She's also missing a leg so God knows what happened to her before she wound up at the shelter.) She's a snuggler when you're sitting down and she requires a lap, but 7 years later she still doesn't like to be picked up. She'll tolerate it most of the time for short periods, but she'd rather you didn't. I don't push the issue. It's not a big deal, I can safely pick her up if I HAVE to, and I'd rather she feel comfortable around me and not worry that something bad is going to happen.