With my arthritis, it's very hard to quilt a large quilt on my machine and paying a LA-er is not in my budget except for very special quilts.
I actually do enjoy QAYG since as each section gets added, you're that much closer to being done. I've done quite a few this way and can handle a queen-size quilt.
The only problem, depending on the method used, is that if the sashing has any design elements (like HST, etc.), that could be a problem. There is a different technique to handle quilts like this.