Four years ago this month, my husband called to me from the bathroom - he was on the floor, I tried to help him and couldn't, so I immediately called 911 and an ambulance was there within minutes. They got him to ER and he got the necessary meds within 3 hr. of the stroke happening. The doctor told me later that his was a case that they would talk about in medical circles for a long time as the drug worked exactly as it should. It was amazing to watch him come back. He passed away about 6 months later from a combination of problems, kidney and heart failure and Alzheimers. But the drug really does work!!