When I first started quilting I only used poly batting,extra high loft to be exact.
However now I only use the poly batting if/when I make a kids quilt that is going to be drug around.
My all time favorite batting to use now is bamboo I use to buy it at Joann's, but I do not think they are carrying it anymore or at least the two stores that is closest to me.
A couple years ago I received a quilt that was made by a group of ladies I had NEVER met in person, we all know each other online at cafemom quilting group. When I received this quilt I cried, later I was told that they even went so far to find some bamboo batting to use since they knew it was my favorite.
When I make quilts for family or special friends I use the bamboo.
I DO have some non bamboo batting but very little at this time.