I have made many quilts with PC. It holds up better than cotton. If it is the newer PC, it looks a feels like cotton and I intermix and never have a problem. It is great for children's quilts as it is non-allergenic, washes beautifully, doesn' t hold stains, mildew, mold as cotton will. I use a poly down batting on these quilts for kids for the same reason. They are not too hot but do keep you warm enough.