You can but I would take the meat off of the bone or at least make sure it's in pieces. I'd also place some turkey or chicken broth in it to give it moistue while it reheats. If it's thawed out you can also put it in a dish w/a very small amount of water or juice; cover it well with plastic wrap and microwave it; do it in increments waiting a few minutes in between each so the the heat distributs in the turkey and this way it won't dry out. Cooking and quilting are my two favorite things to do when I'm not at work.