I'm a pretty frank speaking kind of person, I think I would say something along the lines of " You would take this quilt from a child battling cancer?" or I know your not the type of uncaring person who would even consider taking a/this quilt from a child with cancer(or other ailment) If you still feel the need to have one of these quilts, then I suggest you sign up for one at the hospital/cancer treatment/hospice center. Thank You for your interest. smiling of course. I have not run into anyone like that Thank Goodness! if they are friends of yours, maybe something like " I make these quilts for people/children with cancer, I pray I never have to make one for you"