I cannot create in a messy space, or one that is disorganized. I can work in a disorganized space, but I am not very productive, and I tend to make mistakes (sew wrong blocks together!). My room is not OCD clean, but when I think I'm through with a tool I put it back where it belongs. I straighten up at the end of each day so it is ready to start the next day.
I started doing this is so that I know that 2 yo DGD can't get cutting tools if she comes to visit. Now it's a habit and I've become much more creative and productive.
Besides, if I have clutter I spend my time thinking of ways to organize it instead of sewing.