I have both the Brother and the Janome. The two machines are very, very similar.
Brother - no variable speed control except for what the foot pedal provides. Has needle up/down, automatic thread cutter, a needle threader.
Janome - variable speed control button, needle up/down. Doesn't have automatic thread cutter or needle threader. This particular model takes round needles. (Janome 1600P DB)
My Brother is my "daily driver" and the Janome is on the frame.