Personally, I enjoy handwork, so that's what I do. But I am blown away by some of the amazing machine quilting I've seen on here. I'm not interested in participating in it, but I don't view it as any less of an art form. It requires a different kind of skill, and just because it's different doesn't mean it's wrong.
I do piece by machine. The quilting is my favorite part anyway, so the piecing is a step I have to get out of the way. ;)