I use my domestic sewing machine for quilting. I am lucky enough to also have a quilting frame that I can put it on. Lately though, I find I'm using it table top mode more than on the frame. If I have it on the table, I can make tailor made patterns for each block regardless of the size. On the frame I am limited to the 9" between the rollers.
YES, beautiful quilts can be made on a home sewing machine. If you'd like to check out a fabulous website for this , look up Leah Day's site.
http://www.freemotionquilting.blogspot.com