I would not want to be without a vehicle, so a pull behind would be a must. Motor homes do need to be serviced and they do break down, even new ones :D
Some areas do not have rental car agencies and the nearest can be over a 100 miles away. So if I chose this route? I would be towing a vehicle behind it :D:D:D
You can take a machine and fabric, maybe cutting up kits in advance? Handquilt finished tops? Finding a place big enough to sandwich a big quilt could be a challenge, although some campgrounds may have a community room you could use :D:D:D