Thanks for all the helpful suggestions. This paint was dry on the quilt long before I ever saw it. I tried the alcohol first and it did bring some of it out but also made it bleed a bit. I also tried about every kind of stain stuff I have in the house. I have to give up for now because we are heading out of town in an hour to pick up my son who got the paint on the quilt. One thing I could do is sew a new white block to cover this one and then figure out how to hand quilt to match the rest. I'm sure if I gave it to my MIL to fix she would do it but I hate to have her see what has happened to her precious work.