i'm working on my 3rd hand embroidered quilt- the first one i did was in 1976---and my 35 year old daughter still has it---and her girls have had picnics on it- and played with it-it has held up amazingly well- the second one i gave my mother in law 3 years ago- it is on her bed- i've not heard of any problems-
the third one i have half the blocks done-but have kind of (lost interest) so have not been working on it- i probably should finish it.
as long as you are using good quality fabrics/ materials- and you piece it well there is no reason to think it will not last for many years-
there are tons of hand embroidered quilts in museums....look at all the crazy quilts with all the embroidery--