Absolutely! The materials are full of dyes, pesticides, and heavens knows what from the planting of the cotton, spraying ( such as DDT (which is not banned in other countries), etc. which was the main reason we quit growing cotton in the USA, as nothing really kills the boll weevil), dyes, storage, shipping, warehouses, and the list goes on. We have a few(very few) States trying to revive our cotton crop here in the USA ( like Texas that has lost thousands of acres due to the drought there) the majority of it is grown overseas. It's not about wrinkly, puffy, etc. of the quilt but the cleanliness. imho... Sorry if this is too long...