I use it all of the time as I prefer it to other methods. Do it in a well ventilated area. Use the spray sparingly and you should have few problems. If you are using a polyester batting you should spray the fabric as the spray will melt the polyester slightly and interfere with adhesion. If you are using wool or cotton it is OK to spray the batting. I do one half of the quilt at a time, turn it over and do the next two halves. It is easiest to do if you can pin it to a design wall.
I then generally leave it for a day just to make sure everything is dry and well stuck before quilting.All the best with it.