After trying Frontline, advantage and Adams and about everything else I was ready to give up. I treat my animals and house almost daily this year; nothing works. My dog had emergency surgery this week and when I brought him home I asked the vet; they'd given him a pill that kills them all but it only last 24hours. He was covered when he went in and he'd just had a flea dip the day before. She recommended a new treatment called Simple Guard 3; it's expensive about 100 for 6months but if I add up all of the different things that I'm treating my dogs and house with it's also high. She said the difference in it and Frontline is that with Frontline the fleas have to bite the dog for it to work and with Simple Guard it repells them. In a couple of days they should be dead and them make sure you treat your house and outside if they spend a lot time out there. But since it repells them going outside shouldn't be an issue. I'm really hoping it works. I have two dogs; one very large and one very small so I had to get different treatments for each size; so at almost 200 I really hope it works.