There is a terrific shop in Jonesborough, TN - Tennessee Quilts. It is a little off the path of 81, but worth the slight detour. Mammaw's Thimble is on Papermill in Knoxville. It is very easy to get to from 40, just west of the downtown area. There is another fairly large shop in West Knoxville near the Lovell Road exit of 40 called Gina's Bernina. If you want more specifics, pm me and I'll send some info, although you could probably Google the maps. Oh, and if you are going through Hagerstown, MD to get to 81, there is a great shop there - Wilson's. It is a little north of where 70 joins 81.