Hate to tell you but I think Lancaster is going to be closer than anything I know of! The only places I'm aware of are The Little Shop in Haddonfield, NJ; Olde City Quilts in Burlington, NJ; and Pennington Quilt Works in Pennington, NJ. Next to Pennington Quilt Works is a beautiful yarn shop as well as a bead shop. The last time I was in the yarn shop (Wolly Lamb???) they had beautiful yarn and needlepoint canvases. If you need home dec stuff or garment fabric, Fabric Row in Philadelphia has some great stuff. Nothing to speak of for quilting fabrics though.
Hopefully, someone else here will be able to give your more info on shops on the PA side of the river!