Funny you should ask. I used Chrome for the first time about 1/2 hour ago to sign on to the board, and dumped it immediately. It looked different, I didn't have all the links at the top (missing search, user search, etc) plus there were far more ad's and in annoying places than I get on either Firefox (my preference) or IE (which I use at work).
I might spend more time with Chrome and see if I can set preferences, but so far not impressed.