Right now my index finger on my right hand is killing me. I took a class at the beginning of August on reverse fusible applique where you use a surgical seam ripper held flat on the freezer paper/fabric/fusible combo and cut out the shapes. You have to push fairly hard on the seam ripper and it made my finger really, really sore. I agravated it when I did the hand sewing on a binding a week ago at retreat. Then I hand basted a quilt and after it was quilted I worked the thread ends in and it's back to really sore.
Of course using the mouse and typing don't help it a whole lot either.