Yep.
There are many sellers listing specialty fabrics (Japanese, hand-dyed, Liberty of London, real vintage/antique, etc), and even more offering collections from all the "name" designers, especially the modern fabric lines.
Destashing type items/lots.....there are some. The smart buyers get tired of sifting through all the offerings on eBay and will look at etsy.
But like eBay, you have to somehow get yourself noticed, even if it's to the same cadre of repeat buyers.