Our dog had Cushings Disease, lumps came up all over her body firstly, then she lost big clumps of her fur, she became very bloated, and lost weight. Towards the end, her rear end collapsed and she could barely walk. She was on high doses of tablets and medicine, was having injections at the Vet but in the end nothing could be done. She was 15 years old and I could no longer see her suffer so she went to sleep - 2 years ago this October. I miss her terribly.