If you are talking about keeping it organized while you're creating the blocks, I would use the flannel backed tablecloth method. While I was sewing I'd spread the tablecloth on the floor and when I was done for the day I'd roll it up. The blocks will stay right where you need them to. If you do have a wall you could tack it up on, that would be even better.
If that's not practical, I would work on it in quarters. Divide it down the middle and across the middle. If it's symetrical that will work well.
Either way, it's going to be beautiful!