I trim mine and square up as much as possible if needed and then sew on the binding. I use a generous 1/4 inch seam with a 2 1/4 or 2 1/2" binding, folded over, and the binding is usually "full". I watched an Eleanor Burns show once where she marked the sides of the quilt and then sewed the binding on and then trimmed off the excess quilt. I tried it once and couldn't make it work for me.