I agree with ckcowl. It works just great for long arm or free motion quilting. You just have to make sure you turn the stretchy way of the fleece the opposite way you are pulling or spray baste it down, etc. I have now made over a hundred and prefer it without batting. But, I have customers who insist they want it. All a matter of preference.
You could hand quilt it but it would make large stitches. Works better to tie or machine quilt.
Kids, older people and those taking a nap...just love quilts made this way. Makes the easiest and fastest baby quilt ever.